Last week's Senate 2010 preview is already in need of an update.
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Mel Martinez is abandoning ship after just one term. You may recall that he just narrowly beat Betty Castor in 2004, a year in which the GOP had a decided upper hand. Now he's another Bush victim, and he took some headshots at the Rove Party on his way out the door.

Martinez was in big trouble anyway, and as an open seat the Democratic challenger (probably Wexler) is the clear favorite.
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And I bet Jeb runs.